منابع مشابه
Characterization of a new small cell lung cancer (SCLC) cell line STP54 derived from a metastatic bioptate of a combined type of SCLC with Non-SCLC component.
Small cell lung cancer constitutes 15-20% cases of lung cancers, currently the leading cause of death from malignant diseases. It also causes the demise of >90% of affected individuals in 5 years. We have established a new SCLC cell line STP54 derived from fine needle aspirate of metastatic supraclavicular lymph node of 54 -year-old women for model experiments. The primary tumor was diagnosed b...
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signal transduction pathway has been discovered as a central regulator of embryonic development, tissue maintenance and repair [1]. Moreover, several recent evidences have highlighted its key function in tumorigenesis [2]. In some familial cancers, such as basal cell carcinoma and medulloblastoma, Hh pathway activation represents the initial tumorigenic event, whereas in other human malignancie...
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or metabolites. The presence of anti-neural antibodies in patients with pns has led to the suggestion that the associated neurologic symptoms are a result of antibody-induced inflammatory reactions3. Because of the infrequent incidence of ple, there is a paucity of literature discussing its diagnosis and management. Here, we describe a case of ple in a male patient, and we discuss the syndrome’...
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A few years ago the answer to the question in the title of this review would have been, "unfortunately not much" or even "nothing", likely eliciting knowing nods of agreement from oncologists. For the last 3 decades, SCLC has been notorious for its lack of progress, as drug after drug, over 60 of them, in fact, including inhibitors of VEGF, IGFR, mTOR, EGFR and HGF has failed and fallen by the ...
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This paper uses the weighted L$_1-$norm to propose an algorithm for finding a well-dispersed subset of non-dominated solutions of multiple objective mixed integer linear programming problem. When all variables are integer it finds the whole set of efficient solutions. In each iteration of the proposed method only a mixed integer linear programming problem is solved and its optimal solutions gen...
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ژورنال
عنوان ژورنال: Journal of Thoracic Oncology
سال: 2018
ISSN: 1556-0864
DOI: 10.1016/j.jtho.2018.08.065